AIM: To compare the cyclopentolate hydrochloride eye drops and atropine ophthalmic gel in 12 years old of the following children with hyperopia mydriatic optometry results, in order to assess cyclopentolate hydrochloride drops of clinical value to use eye drops in hyperopia refraction.

METHODS: Fifty-one cases(102 eyes), aged 2-12 years old children with hyperopia, first with 10g/L cyclopentolate hydrochloride eye drops 5 times continuously after optometry, interval of 1d, with 10g/L atropine sulfate eye 3d mydriatic optometry gel for eyes. Analysis and comparison of two kinds of cycloplegic refraction in different groups of optometry results and systemic adverse reactions.

RESULTS: Thirty-one eyes with gentle hyperopia refraction results were no statistical difference(P>0.05), 39 eyes with moderate hyperopia refraction results were no statistical difference(P>0.05), 32 eyes with high myopia refraction results were no statistical difference(P>0.05). Systemic adverse reactions of the 10g/L cyclopentolate hydrochloride eye drops were 2%, 10g/L atropine eye gel systemic adverse reaction rate was 8%.

CONCLUSION:Cyclopentolate hydrochloride eye drops is a new cycloplegic with fast onset, strong action, short duration, safe and effective, which can be wildly used clinically.