AIM: To analyze the effect of modified trabeculectomy in the treatment of neovascular glaucoma.

METHODS: There were 44 cases of neovascular glaucoma enrolled during June 2008 to December 2012. They were randomly divided into experimental group(22 cases)and control group(22 cases). The experimental group were treated with the modified trabeculectomy, and the control group were treated with cyclocryotherapy. Therapeutic effect and complications between two groups were compared.

RESULTS: Introocular pressure in both groups were significantly lower after treatment than before treatment(P<0.01), but there was no obvious difference between two groups(P>0.05). The total effective 21 cases(95%)in experimental group was higher than that in the control group 16 cases(73%)and the difference had statistically significance(χ²=7.3789, P<0.05). At the same time, the incidence of complications and severity in control group were significantly higher than that in the experimental group(P<0.05).

CONCLUSION: For patients with neovascular glaucoma, modified trabeculectomy can effectively reduce the intraocular pressure, and significantly improve the treatment success rate, as well as reduce the occurrence of adverse reactions. It is a safe and effective method, so modified trabeculectomy should be applied widely in clinical practice.