Behcet病患者血清TNF-α和IFN-γ及MCP-1水平的研究
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广州市中医药科技项目(No. 20132A011014)


Research on the serum levels of TNF-α, IFN-γ and MCP-1 in patients with Behcet's disease
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The Traditional Chinese Medicine Project of Guangzhou(No. 20132A011014)

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    摘要:

    目的:探讨Behcet病(Behcet's disease,BD)患者血清TNF-α、IFN-γ、MCP-1的水平。

    方法:BD患者25例,对照组为健康志愿献血员30例,抽取血清检测TNF-α、IFN-γ、MCP-1等指标。

    结果:BD活动期患者TNF-α、IFN-γ、MCP-1均高于健康对照组,差异有统计学意义。

    结论:BD活动期患者TNF-α、IFN-γ、MCP-1异常升高,可能与BD的发病机制有关。

    Abstract:

    AIM: To study the serum levels of TNF-α, IFN-γ and MCP-1 in patients with Behcet's disease(BD).

    METHOS: Twenty-five patients with BD as study group and 30 normal volunteers as control group were inclued in the study. Serum levels of TNF-α, IFN-γ and MCP-1 were measured.

    RESULTS: Serum levels of TNF-α, IFN-γ and MCP-1 were significant higher in active BD patients than in normal controls.

    CONCLUSION: Our results suggest that serum levels of TNF-α, IFN-γ and MCP-1 abnormally increased in active BD paiteins. The higher expression may play a role in the pathogenesis of BD.

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袁永刚,梁纳,马胜生,等. Behcet病患者血清TNF-α和IFN-γ及MCP-1水平的研究.国际眼科杂志, 2014,14(4):780-781.

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  • 收稿日期:2013-11-12
  • 最后修改日期:2014-03-18
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  • 在线发布日期: 2014-03-24
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