AIM: To observe and analyze the change situation of hemorheology, Aβ, β-EP, Hcy and ocular hemodynamics indexes of patients with glaucoma.

METHODS: Sixty patients with glaucoma in our hospital from November 2011 to October 2013 were the observation group, 60 healthy people were the control group, then the hemorheology, Aβ, β-EP, Hcy and ocular hemodynamics indexes of two groups were detected and compared, then the detection levels of patients with different Richardson stages were compared.

RESULTS: The hemorheology, Aβ, β-EP, Hcy and RI of observation group were all significantly higher than those of control group, and the PSV and EDV were obviously lower than those of control group, the fluctuation of patients with higher Richardson stages were all bigger than those of patients with lower Richardson stages,all P<0.05, there were all significant differences between those comparison indexes.

CONCLUSION: The change of hemorheology, Aβ, β-EP, Hcy and ocular hemodynamics indexes of patients with glaucoma are great, and the blood supply of patients with higher stages are worse, and the serum related indexes were higher.