AIM: To investigate the relationship between the macular retinal thickness and diopter, dominant eye, axial length.

METHODS: Totally 128 patients with high myopia group 180 eyes were selected, including the dominant eye in 79 eyes, the non dominant eye in 101 eyes. OCT was applied to measure macular and peripheral retinal thickness and A-mode ultrasonic diagnostic equipment to axial length. Another 112 patients with emmetropia group in 180 eyes, including the dominant eye in 106 eyes and the non dominant eye in 74 eyes served as control. Obtained data were statistically analyzed.

RESULTS: The average length of ocular axis in patients with high myopia(29.57±1.57)mm were significantly prolonged, compared with the mean axial length in normal group(24.13±0.90)mm(P<0.05). The length of ocular axis and the retinal thickness of foveal inner ring area(from the foveal region of 1-3mm)above(S₁), below(I₁), temporal(T₁)and foveal outer ring area(from the foveal region of 3-6mm)above(S₂), below(I₂), nasal(N₂), temporal(T₂)existed correlation, while there was no correlation with macular central and nasal foveal inner ring area(N₁)retinal thickness. The retinal thickness of macular central area and each partition in high myopia group were obviously thinner than emmetropia group(P<0.05). There was no statistical significance(P>0.05)between dominant and non dominant eye macular retinal thickness in high myopia.

CONCLUSION: The detected values of high myopia macular retinal thickness by OCT are lower than emmetropia group. There is a negative correlation between the ocular axial length and macular retinal thickness above(S₁), below(I₁), temporal(T₁), above(S₂), below(I₂), nasal(N₂), temporal(T₂)with high myopia. Ocular dominance and non dominant eye macular retinal thickness with high myopia have no obviously difference.