AIM:To analyze the low energy laser photocoagulation under treatment of central serous chorioretinopathy(CSC)correlation of clinical effect and visual acuity with leakage location.

METHODS:Using low energy laser on the leakage point in the parafoveal and 53 cases of central serous chorioretinopathy patients underwent laser closed, drug treatment group and 33 cases as control. Comparison of two groups was observed before and after treatment in patients with symptoms, ocular fundus, fundus fluorescein angiography(FFA)changes, fundus optical coherence tomography technology(OCT)examination, visual acuity improved in degree, and the relationship between the cure rate, relapse rate. All 126 cases were associated with visual leakage location analysis.

RESULTS:The cure rate of lasercomparison: 4 weeks after operation, the cure rate was 92.5%. The drug therapy group at 4 weeks after treatment cure rate was 30.3%.The two groups were compared(P<0.01), and there was significant difference. The laser group and treatment group after treatment in 2 weeks, 4 weeks, in March June, and there was significant difference(P<0.01). The medicine group the recurrence rate was 12.1%, the lasertreatment group and recurrence rate was 11.3%. The two groups were compared, no significant difference(P>0.05). Nonparametriccorrelation analysis method to compare the relationship between visual acuity and fluorescence leakage point location, the correlation coefficient(r=0.216, P=0.0001), there is a positive linear correlation between.

CONCLUSION:The leakage point in the parafoveal outside in early stagelaser in the treatment of low energy laser, can shorten the course of disease, improve the cure rate of visual acuity and clinical, and improve the visual quality, but can not reduce the recurrence rate. There is a positive correlation between visual acuity and leakage location, clinicalguidance for prognosis and treatment.