AIM: To investigate the correlation between myopic refractive error and relative factors, including the corneal refractive power, posterior refractive power, axial length, corneal asphericity coefficient Q value, central cornea thickness(CCT)and intraocular pressure(IOP).

METHODS:According to the degree of myopia measured by subjective refraction, 138 myopia patients were divided into three subgroups: mild group(-1.00D--3.00D), moderate group(-3.25D--6.00D), high group(>6.00D). The Pentacam anterior segment tomographer(Germany, Oculus Company)was used to measure the corneal refractive power, posterior refractive power, and corneal asphericity in the right eye. IOP, CCT and axial length were measured by a non-contact tonometer and A-scan ultrasonic, respectively. The data was analyzed with a Pearson correlation analysis and one-way ANOVA.

RESULTS: The myopic refractive error was negatively correlated with the axial length(r=-0.682, P<0.001), but was not correlated with the corneal refractive power(r=0.009, P=0.925). The axial length was negatively correlated with corneal refractive power(r=-0.554, P<0.001). The myopic refractive error was postively correlated with the Q value(r=0.674, P<0.001), which was negatively correlated with the IOP(r=-0.375, P=0.01). There was no significantly correlation between the myopic refractive error and CCT, IOP(r=-0.138, P=0.141; r=-0.121, P=0.157).

CONCLUSION:The corneal refractive power plays the role of emmetropization during the development of myopia. There is clinic significance for the correlation between Q value and refractive error, IOP to guide the corneal refractive surgery.