AIM: To study and observe the changes of serum, aqueous humor and tear IL-2, sIL-2, NO, TAC, and SOD of patients with cataract.

METHODS: Totally 60 patients with cataract in our hospital from November 2011 to September 2013 were included as the observation group, and 60 patients with eye traumas were as the control group. The serum, aqueous humor and tear IL-2, sIL-2, NO, TAC, and SOD of two groups were detected and compared, and the detection levels of patients with different stages were compared.

RESULTS: The serum, aqueous humor and tear IL-2, TAC, and SOD of observation group were all lower than those of control group, the sIL-2 and NO were all higher than those of control group. The serum, aqueous humor and tear detection levels of patients at different stages had obvious differences, and the aqueous humor IL-2 were lower than those of serum and tear, the sIL-2 were higher than those of serum and tear, with statistically significant differences.

CONCLUSION: The change of serum, aqueous humor and tear IL-2, sIL-2, NO, TAC, and SOD of patients are all great, and the influence of the stages for those indexes are great too, the inflammatory response state of aqueous humor are more obvious.