两种手术方法治疗绝对期新生血管性青光眼的疗效对比
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Study on the efficacy between cyclocryotherapy combined trabeculectomy and single cyclocryotherapy for neovascular glaucoma
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    摘要:

    目的:对比观察睫状体冷凝联合复合式小梁切除术与单用睫状体冷凝技术治疗绝对期新生血管性青光眼(neovascular glaucoma, NVG)的临床效果。

    方法:收集我院2012 -02/2013-06间收治的82例绝对期新生血管性青光眼病例。随机分为观察组和对照组,各41例。对照组给予睫状体冷凝术治疗; 观察组患者给予睫状体冷凝联合复合式小梁切除术治疗。对两组术后视力、眼压和并发症进行观察。

    结果:观察组患者术后6mo视力提高率为61.0%,显著性高于对照组(41.5%),差异有统计学意义(χ2=3.843,P=0.018); 观察组患者术后眼压显著性低于对照组,差异有统计学意义(P<0.05); 观察组术后眼球疼痛、前房出血和角膜水肿并发症发生率为9.8%,12.2%,9.8%,显著性低于对照组的51.2%,60.9%,48.8%,差异有统计学意义(χ2=7.594,P=0.007; χ2=9.276,P=0.000; χ2=6.835,P=0.013); 两组球结膜水肿、前房渗出、浅前房和眼球萎缩并发症的发生率比较无统计学意义(P>0.05)。

    结论:相比于单用睫状体冷凝术,睫状体冷凝联合复合式小梁切除术治疗NVG具有降眼压效果好、术后并发症少、成功率高的优点,值得推广。

    Abstract:

    AIM: To investigate the clinical efficacy of cyclocryotherapy combined trabeculectomy and single cyclocryotherapy for neovascular glaucoma(NVG).

    METHODS:Totally 82 patients with NVG from February 2012 to June 2013 in our hospital were selected and randomly divided into observation group and control group, each 41 cases. Patients in control group were given single cyclocrytherapy, and patients in observation group were given cyclocryotherapy combined trabeculectomy. The visual acuity, intraocular pressure and postoperative complications of two groups were observed.

    RESULTS: After postoperative six months, the improvement rate of visual acuity in observation group was 61.0%, which was significantly higher than that of control group(41.5%), the difference was statistically significant(χ2=3.843, P=0.018). Intraocular pressure of observation group was significantly lower than that of control group, the difference was statistically significant(P<0.05). The complication rates(eye pain, hyphema, and corneal edema)of observation group were 9.8%, 12.2%, and 9.8%, which were significantly lower than that of control group(51.2%, 60.9%, and 48.8%), the difference was statistically significant(χ2=7.594,P=0.007; χ2=9.276,P=0.000; χ2=6.835,P=0.013). The difference of two groups was not statistically significant on complications of conjunctival edema, anterior chamber exudation, shallow anterior chamber, and eyeball atrophy(P>0.05).

    CONCLUSION: Compared with single cyclocryotherapy, cyclocryotherapy combined trabeculectomy has advantages of low intraocular pressure, less postoperative complications, and high success rate, so it is worthy of promotion.

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王千.两种手术方法治疗绝对期新生血管性青光眼的疗效对比.国际眼科杂志, 2014,14(9):1638-1640.

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  • 收稿日期:2014-05-02
  • 最后修改日期:2014-08-13
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  • 在线发布日期: 2014-08-19
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