AIM: To evaluate the clinical effect of laser in situ keratomileusis(LASIK)with the corneal flap created by FEMTO LDV femtosecond laser for myopia.

METHODS: The corneal flap was created by the FEMTO LDV femtosecond laser, and the thickness of the flap was 110μm. A total of 143 myopic patients(283 eyes)were treated with the EC5000-CXIII element laser. The optometry of the eye, best corrected visual acuity(BCVA)the thickness of the cornea, and ObscanⅡ were examined before the operation. The thickness of the flap was calculated by measuring the thickness of corneal bed during the operation in 35 eyes. The conditions of the corneal flap, complications, uncorrected visual acuity(UCVA), diopter, corneal topography were observed during and after the operation and were checked for 3mo follow-up.

RESULTS: During the operation, it appeared small flap(diameter<5mm)in 3 eyes, corneal margin incised incompletely in 5 eyes and incision bleeding in 8 eyes. Postoperative subconjunctival hemorrhage appeared in 6 eyes. The thickness of corneal flap in 35 eyes was 108.75±8.52μm(98-117μm)and the error was 6.49±8.62μm(3-12μm). There was no significant difference between the actual flap thickness and the preset flap thickness(P>0.05). The average equivalent spherical refractive was -0.29±0.47(-1.50 to +1.00)DS after the operation for 3mo and the UCVA met or exceeded preoperative BCVA in 251 eyes(88.7%).

CONCLUSION: The operation of myopia by LASIK flap created by FEMTO LDV femtosecond laser has fewer complications, and the effect is definite and safe.