AIM:To investigate the choice of different treatments for malignant glaucoma.

METHODS: In this retrospective case series, 21 malignant glaucoma patients(21 eyes)admitted in Wuhan General Hospital of Guangzhou Military Command from May 2012 to May 2013 were analyzed. Sixteen eyes(76%)developed malignant glaucoma after filtration surgery, 3 eyes(14%)after EX-PRESS glaucoma filtration device, 2 eyes(10%)after glaucoma filtration Ahmed valve implantation. Main Outcome of corrected visual acuity, intraocular pressure(IOP), anterior chamber depth and complications were detected.

RESULTS: IOP recovered by drug control in 13 eyes, anterior chamber depth. Four eyes were treated by vitreous water-bag aspiration combined with anterior chambers reconstructing. Two eyes were treated by cataract extraction and intraocular lens implantation. Two eyes were treated by posterior capsule excision combined with anterior vitrectomy. IOP before and after treatment was 29.81±4.98, 12.71±3.77mmHg, respectively(P=0.00). Anterior chamber depth before and after treatment was 0.41±0.34, 2.13±0.54mm, respectively(P=0.00). Corrected visual acuity before treatment was 0.19±0.17, after treatment was 0.20±0.16(P=0.36). Except for vitreous hemorrhage in 1 eye, there were no ocular or systemic adverse events observed in all patients.

CONCLUSION: It is good to diagnose malignant glaucoma in early period, and treated it step by step. For this can reduce IOP and restore anterior chamber.