AIM: To evaluate the relationship between the morphologic changes of central serious chorioretinopathy(CSCR)and recovery of visual acuity visual acuity(VA).

METHODS: Thirty-eight eyes of thirty-eight patients with CSCR were studied and divided according to best corrected visual acuity(BCVA). Group 1, n=17(45%), VA 6/6-6/9(logMAR 0～0.176); Group 2, n=19(50%), VA 6/9-6/18(logMAR 0.176～0.477); Group 3, n=2(5%), VA less than 6/18(logMAR 0.477). All patients inspected by spectral-domain optical coherence tomography(SD-OCT).

RESULTS: The mean age of the patients was 42.50±5.41years, the mean logMAR VA was 0.176±0.0185, retinal pigment epithelium(RPE)detachments in 21 eyes(55%), including single RPE detachments in 14 eyes(67%), and multiple confluent RPE detachments in 7 eyes(33%). Small bulge of RPE in 7 eyes(18%), granular deposition epi-RPE in 5 eyes(13%). The mean subretinal fluid height at the fovea was 259.11±128.78μm. The average photoreceptor lengths were 70.1±9.08μm, 81.6±8.16μm, and 91.9±8.03μm in groups 1, 2, and 3, respectively, the mean subretinal fluid height at the fovea was 66.5±8.13μm, 67.8±7.49μm, and 58.6±7.26μm after 6mo, respectively. The mean outer nuclear layer thickness during the active stage was 93.10μm and it was 75.69μm after 6mo(P=0.012)

CONCLUSION: In the acute CSCR, VA showed statistically significant association with greater dimensions of subretinal fluid-particularly, greater subretinal fluid height and thinning of the outer nuclear layer at the fovea. The type of pigment epithelium detachment(PED), location, or fiber deposition has nothing to associate with VA. In resolved CSCR, VA has a significant associated with a persistently thinner outer nuclear layer.