AIM: To analyze the reasons of impaired vision after LASIK and explore its preventive treatment measures preliminarily.

METHODS: In this retrospective study, 175 eyes of 134 patients whose vision was decreased after LASIK were included. The constituent ratio of every reason was counted and uncorrected visual acuity(UCVA)between pre-treatment and post-treatment were compared by paired t-test respectively.

RESULTS: The overall incidence of impaired vision after LASIK was 1.86%. The constituent ratio of regression was 51.43% and UCVA increased from 0.61±0.22 to 0.90±0.38(t=8.00, P<0.001)after treatment. The constituent ratio of punctate corneal epithelial defect was 32.57% and UCVA increased from 0.60±0.19 to 1.20±0.24(t=20.00, P<0.001)after treatment. The constituent ratio of accommodative spasm was 5.14% and UCVA increased from 0.76±0.21 to 1.32±0.22(t=8.14, P<0.001)after treatment. The constituent ratio of corneal flap shift and gauffer was 4% and UCVA increased from 0.29±0.26 to 1.24±0.28(t=6.33, P<0.001)after treatment. The constituent ratio of corticosteroid-induced ocular hypertension was 4% and UCVA increased from 0.57±0.05 to 1.0±0.16(t=2.53, P<0.05)after treatment. The constituent ratio of fundus lesions and diffuse lamellar keratitis(DLK)was 2.86% and UCVA all increased by different degrees after treatment.

CONCLUSION: The reasons of impaired vision after LASIK are many and varied. These cases could recover their vision by discovery and treatment in time, and the appropriate preventive measures were essential.