高渗葡萄糖在白内障术后角膜水肿的疗效分析
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Efficacy of hyperosmotic glucose in treatment of corneal edema after cataract surgery
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    摘要:

    目的:探讨高渗葡萄糖在白内障术后中重度角膜水肿的疗效。

    方法:临床病例随机对照研究。选取小切口手法白内障联合人工晶状体植入手术术后Ⅱ级及以上白内障患者80例80眼,随机分为试验组(高渗糖组)和对照组,对照组采用妥布霉素地塞米松滴眼液等常规治疗,试验组在治疗组的基础上加用500g/L高渗葡萄糖液,观察术后角膜水肿程度及消退情况。采用SPSS 17.0统计软件进行统计学分析。

    结果:两组患者年龄、性别、白内障核硬度及术后第1d角膜水肿程度,两组患者比较差异均无统计学意义(P>0.05),角膜水肿消退情况显示,实验组角膜水肿消退平均时间为4.95±3.62d,对照组为6.80±3.33d,明显少于对照组(t=8.55,P=0.00)。

    结论:高渗葡萄糖滴眼液可加快白内障术后中重度角膜水肿的消退,是一种治疗白内障术后中重度角膜水肿比较安全、有效的方法。

    Abstract:

    AIM:To explore clinical efficacy of hyperosmotic glucose after cataract surgery.

    METHODS: Eighty eyes(80 cases)with II level and above grades corneal edema after small incision cataract operation were enrolled. They were randomly divided into treatment group and control group. Control group used TobraDex eye drops and other conventional treatment and the treatment group received hyperosmotic glucose(500g/L)with the bases of the control group. The regression of corneal edema was observed by slit lamp microscope. SPSS 17.0 statistical software was used for statistical analysis.

    RESULTS: The level of corneal edema at the first day after surgery, age, sexuality and nuclear hardness in the treated group were compared with those in the control group, the differences were without significances(P>0.05). Disappearance time of corneal edema was 4.95±3.62d of the treatment group, and was 6.80±3.33d of the control group, the treatment group was better than control group(t=8.55, P=0.00).

    CONCLUSION: Hyperosmotic glucose has exact and obvious efficacy for early corneal edema after cataract surgery.

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邵玉妹,杨建,吴兵.高渗葡萄糖在白内障术后角膜水肿的疗效分析.国际眼科杂志, 2015,15(2):329-330.

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  • 收稿日期:2014-08-28
  • 最后修改日期:2015-01-20
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  • 在线发布日期: 2015-01-30
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