AIM:To evaluate the efficacy of combined pranoprofen eye drops and artificial tears on the treatment of mild to moderate dry eye syndrome after trabbeculectomy.

METHODS: This prospective case control study included 63 cases(63 eyes)of patients with mild to moderate dry eye syndrome after trabbeculectomy in our hospital from November 2013 to June 2013. All subjects were randomly divided into two groups. Observation group was treated with combined pranoprofen eye drops and artificial tears and control group received simple artificial tears marking the eyes at 1, 2, 4wk. The patient's symptoms, signs, BUT, SⅠt, and FL were observed before treatment and 1, 2, 4wk after treatment.

RESULTS:After 2wk, the symptoms of observation group were improved, there was statistically significant difference(P<0.05). FL difference of each group was statistically significant(P<0.05); After 4wk, symptoms and signs were improved. There was statistically significant difference(P<0.05). The BUT of the observation group and corneal FL scores of two groups showed significant differences(P<0.05).

CONCLUSION: Artificial tears joint pranoprofen eye drops has good curative effect in the treatment of mild to moderate dry eye syndrome after trabbeculectomy.