Obstructive sleep apnea hypopnea syndrome(OSAHS)is a disorder characterized by repeated episodes of collapse of the upper airway during sleep,and ultimately lead to the repeated cycle of night intermittent hypoxemia. Recently,an association of OSAHS and diabetic retinopathy(DR)has been reported. This paper reviewed the correlation between OSAHS and DR from clinical relationship, the relevant examinations and its possible mechanism of action.