Abstract:AIM: To study the effect of Qi Ming granule intervention on retinal function in the patients with simplex diabetic retinopathy.
METHODS: Eighty cases of simple diabetic retinopathy patients in our hospital from May, 2012 to May, 2014 were randomly divided into two groups, and each group had 40 cases. The control group was received conventional treatment combined with compound Xueshuantong capsule. The observation group was given conventional treatment combined with Qi Ming granule treatment.
RESULTS: The total efficiency(95%)of the observation group was higher than that(80%)of the control group, and there was statistically significant difference(P<0.05). After treatment, visual field mean sensitivity of the observation group was higher than that of the control group, and there was statistically significant difference(P<0.01). After treatment, patients with O1 and O3 latency, the observation group was compared with the control group, and there was statistically significant difference(P<0.05). After treatment, patients with O1, O3, and O4 amplitude, the observation group was compared with the control group, and there was statistically significant difference(P<0.01). After treatment, fibrinogen and blood viscosity of low shear, plasma viscosity, and whole blood viscosity of the observation group were lower than those in the control group, and there were statistically significant differences(P<0.01). After treatment, total cholesterol and low density lipoprotein cholesterol of the observation group was less than those in the control group, and there were statistically significant differences(P<0.05). After treatment, the patients in the observation group serum insulin-like growth factor-1 and vascular endothelial growth factor serum insulin levels were lower than those of the control group of patients, and there were statistically significant differences(P<0.01).
CONCLUSION: Qi Ming granule can delay the progress of the simplex diabetic retinopathy, and it has a good effect on the treatment of early diabetic retinopathy and can improve the function of retina.
