AIM: To observe the clinical effect of houttuynia cordata eyedrops combined with basic fibroblast growth factor(bFGF)eyedrops in treating dry eye after keratorefractive surgery.

METHODS: Respectively, 117 patients(204 eyes)were randomly assigned to treatment group(61 patients, 113 eyes)andthe control group(56 patients, 91 eyes). In control group, the eyes were used bFGF eyedrops four times a day, one drop at a time, and the treatment group was used bFGF eyedrops and houttuynia cordata eyedrops. After 2wk and 4wk of treatment, clinic symptom, Shirmer Ⅰ test(SⅠt), break-up time of tear film(BUT)and fluorescence staining were recorded respectively.

RESULTS: After 2wk and 4wk of observation, the clinic symptom of two groups was both improved. SⅠt, BUT and fluorescence staining scores in the treatment group were significantly better than those in control group(P<0.05). After 4wk, the total effective rate of treatment group was 98%, while that in the control group was 90%, there was significant difference between the two groups(P=0.011).

CONCLUSION: Houttuynia cordata eyedrops can improve the effect of bFGF eyedrops in treating dry eye after keratorefractive surgery.