新疆哈萨克族白内障患者术前结膜囊细菌培养及药敏试验分析
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Investigation and analysis of bacterial spectrum and drug sensitivity test in conjunctival sac of cataract patients of Kazak
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    摘要:

    目的:了解哈萨克族白内障患者结膜囊带菌和药敏情况。

    方法:收集538例哈萨克族白内障患者的结膜囊分泌物进行细菌培养、鉴定和药敏试验。

    结果:538份标本细菌培养阳性214例,阳性率39.8%。病原菌的种类以革兰氏阳性球菌为主(88.3%),其中表皮葡萄球菌最常见(66.4%),其次是微球菌(9.8%)。性别对哈萨克族白内障患者结膜囊带菌率无影响,而年龄、居住地对带菌率有影响(≥60岁人群结膜囊带菌率明显高于40~59岁人群,农牧区人群结膜囊带菌率明显高于城市人群)。分离出的革兰氏阳性球菌对青霉素、红霉素、四环素和氯霉素的敏感性较差,耐药率>70%; 而对万古霉素、替考拉宁、利福平、妥布霉互和阿米卡星较敏感,耐药率<20%。

    结论:革兰氏阳性球菌是哈萨克族白内障患者结膜囊最常见的菌种,尤其是表皮葡萄球菌; 结膜囊带菌情况与受检者的年龄和居住地域相关。临床上应严格掌握抗菌药物使用的适应证,以减少细菌耐药的发生。

    Abstract:

    ATM: To analyze bacterial spectrum and drug sensitivity in conjunctival sac of cataract patients of Kazak.

    METHODS:A total of 538 cases of conjunctival sac secretion in cataract patients of Kazak were collected. The samples were cultured and their sensibilities to antibiotics were tested.

    RESULTS: The bacterial culture was positive in 214 cases. The positive rate was 39.8%. The variety of pathogenic bacteria were mainly made up of gram positive cocci(88.3%), and most of them were Staphylococcus epidermidis(66.4%), followed by Micrococcus(9.8%). Sex had no effect on conjunctival bacteria rate in the cataract patients of Kazak, while age, place of residence had an effect on camier rate. The camier rate of conjunctival bacteria was significantly higher in people over 60 years old than that in people with age between 40 to 59 years old. And the people from city had a significant lower bacteria positive rate than those from countryside and pastoral. Most of grams were sensitive to Vancomycin, Teicoplanin, Rifampicin, Duly cloth mildew mutual and Amikacin, the tolerance was less than 20%, and they usually had higher tolerance to Penicillin, Erythromycin, Tetracycline and Chloramphenicol(>70%).

    CONCLUSION: Gram positivecocci is the most common bacteria in conjunctival sac in cataract patients of Kazak. Staphylococcus epidermidis was most common, followed by Micrococcus. The germ-carrying rate of conjunctival SAC in Kazakh population is associated with the patient's age and area of residence. The clinical use of antibacterial drugs should be strictly grasp the indications, to reduce the incidence of bacterial resistance.

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宋林,姚春华,魏文斌,等.新疆哈萨克族白内障患者术前结膜囊细菌培养及药敏试验分析.国际眼科杂志, 2015,15(3):528-530.

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  • 收稿日期:2014-12-08
  • 最后修改日期:2015-02-27
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  • 在线发布日期: 2015-03-09
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