AIM: To investigate the distribution and related factors of corneal spherical aberration in the age-related cataract patients, and to provide a scientific basis for the application of aspheric intraocular lens(IOL)in cataract surgery patients.

METHODS: Retrospective study of 509 age-related cataract patients of 610 eyes in our hospital. Corneal spherical aberration, corneal curvature, corneal astigmatism and corneal Q-value were examined by iTrace visual function analysis. Statistical software SPSS16.0 was used to analyze statistically.

RESULTS: The range of corneal spherical aberration was 0～1.800μm. The mean coefficient of corneal spherical aberration was 0.266±0.010μm. Corneal spherical aberration was no significantly correlation with age, corneal curvature, corneal astigmatism(r=0.71, 0.56, 0.93, P>0.05). There was positive correlation between corneal spherical aberration and Q-value(r=0.086, P=0.03).

CONCLUSION: Corneal spherical aberration varied greatly among age-related cataract patients. The choice of asphericity intraocular lens should be a matter of personal choice.