方法：回顾性分析2012-03/2013-03到我院眼科就诊33例33眼难治性青光眼患者临床资料，所有患者均行半导体激光经巩膜睫状体光凝术，激光能量1 000～3 000mW，时间2 000～3 000ms，击射范围270°～360°，击射点20～40点。随访观察并记录患者临床症状、视力、眼压、眼前节及并发症，随访时间为6mo。

结果：最后随访时32例(97%)的患者眼部症状明显缓解或消失； 术前平均眼压为50.26±9.37mmHg，最后随访6mo时平均眼压下降为18.38±8.73mmHg，治疗前后眼压具有统计学意义(P<0.05)。2例(6%)术后3mo时眼压再次升高，给予再次激光治疗，术后并发症为前房炎症反应9例(27%)，前房出血5例(15%)，结膜下出血2例(6%)，结膜充血水肿12例(36%)，眼球萎缩1例(3%)。

结论：半导体激光经巩膜睫状体光凝术治疗难治性青光眼是一种简便、降压显著、痛苦小、安全有效的方法。

METHODS: A retrospective review of 33 patients(33 eyes)whose eyes were diagnosed as refractory glaucomatous from March 2012 to March 2013 were treated with Tscpc(energy 1 000～3 000mW, time 2 000～3 000ms, range 270°～360°, count 20～40). Ocular symptoms, visual acuity, and intraocular pressure(IOP), ocular protomerite and complications were observed after Tscpc. Patients were followed up 6mo.

RESULTS: The pain sense of 32 patients(97%)disappeared or remarkably relieved at the final follow up. Mean pre-operative IOP was 50.26±9.37mmHg, which was significantly different from the final follow-up 6mo mean IOP 18.38±8.73mmHg(P<0.05). At three month postoperative, IOP of 2 cases(6%)was rise, and those patients were retreated with Tscpc. Complications included inflammation in anterior chamber reaction in 9 cases(27%), hyphema 5 cases(15%), conjunctival hemorrhage 2 cases(6%). Bulbar conjunctival congestion and edema 12 cases(36%), and atrophy of eyeball 1 case(3%).

CONCLUSION: Semiconductor laser transscleral cyclophotocoagulation is a simple, safe and effective method in the treatment of refractory glaucoma.