AIM: To evaluate the therapeutic effects of mitomycin C(MMC)subconjuctival injection with needling revision on dysfunctional filtering blebs after trabeculectomy for glaucoma.

METHODS: MMC 0.1mL(0.2mg/mL)subconjuctival injection with needling revision was performed on 39 eyes of 36 patients with dysfunctional filtering blebs 2～12wk after trabeculectomy for glaucoma. An average of 1.31±0.58 times of treatment was performed. The intraocular pressure(IOP), blebs and complications were observed and follow up was conducted for 3mo.

RESULTS: Three months after treatment, the mean IOP was 15.8±6.6mmHg, significantly lower than that of before treatment(27.4±5.7mmHg). There were 32 eyes with successful filtering blebs, with the success rate of 82.1%. Subconjuctiva hemorrhage occurred in 7 eyes, shallow anterior chamber and hypotony occurred in 1 eye, No such complications as leakage of the wound and choroidal effusion were observed during the follow up.

CONCLUSION: MMC subconjuctival injection with needling revision is a safe, simple and effective method for dysfunctional filtering blebs after trabeculectomy.