AIM: To explore the differences of anterior segment parameters in the patients with fellow eyes of unilateral acute angle-closure glaucoma(AACG), primary angle-closure suspects(PACS)and normal group.

METHODS: Twenty-six eyes of 26 patients with fellow eyes of AACG, 28 eyes of 28 age- and gender-matched PACS and 34 normal eyes were imaged using optical coherence tomography(OCT)and pentacam scheimpflug system(Pentacam). Anatomical parameters including central corneal thickness(CCT), corneal volume(CV), pupillary diameter(PD), central anterior chamber depth(CACD), peripheral anterior chamber depth(PACD), anterior chamber volume(ACV)and anterior chamber angle(ACA)were obtained from Pentacam. Iris thickness(IT750,IT2 000), cross-sectional area(IS), volume(IV)and angle opening distance 500(AOD500)were estimated using OCT combined with a computer image processing. Statistic analysis was performed with SPSS.

RESULTS: There were no significant differences in corneal parameters(CCT, CV), PD and iris values(IT750, IT2 000, IS, IV)among the three groups(P>0.05). Compared with the fellow eyes of AACG and PACS, normal eyes had larger ACV, wider AOD500 and ACA, deeper CACD and PACD(P<0.05). No anatomical difference was observed between the fellow eyes of AACG and PACS(P>0.05). Using the fellow eyes of AACG as the standard to predict high risk of angle closure, areas under the receiver operating characteristic curve of the above parameters were all less than 0.7.

CONCLUSION: All the anterior segment parameters are no different significantly between the fellow eyes of AACG and PACS. They may be notaccurate criteria for determining high risk group of PACS.