AIM: To observe of cataract phacoemulsification and intraocular lens implantation in patients with postoperative tear film, and to explore its clinical significance.

METHODS: A total of 106 patients(140 eyes)undergone phacoemulsification were randomly chosen. Subjective dry foreign body sensation were observed at six nodes of period 1d, 1, 2, 3wk, and 1mo. Corneal fluorescein(FSC), basal tear secretion(SIT)and tear film break-up time(BUT)were used to detect functional changes of the tear film. And the correlation between tear film stability and corneal sensitivity was analyzed.

RESULTS: Dry eye cumulative score of postoperative 1d, 1, 2wk was higher than preoperative(t=8.53, P=0.000; t=6.27, P=0.000; t=9.02, P=0.000). There was no significant difference in dry eye cumulative score at postoperative 3wk, 1mo compared with preoperative(t=1.91, P=0.824; t=1.27, P=0.069). Corneal epithelial fluorescein staining points of postoperative 1d, 1, 2wk were increased compared with preoperative(t=11.64, P=0.000; t=9.61, P=0.000; t=8.87, P=0.001). There was no significant difference in corneal epithelial fluorescein staining points of postoperative 3wk and 1mo compared with preoperative(t=2.52, P=0.746; t=1.16, P=0.094). Corneal sensitivity detection values of postoperative 1d, 1, 2wk were significantly higher than that of preoperative(t=9.61, P=0.000; t=9.27, P=0.000; t=11.39, P=0.024), and there was no difference postoperative 3wk and 1mo compared with preoperative(t=1.19, P=0.562; t=2.17, P=0.501).

CONCLUSION: Phacoemulsification with intraocular lens implantation will reduce the tear film stability in the short term, but after a long rest will be improved to a certain extent.