Smart Plug泪小管塞治疗水液缺乏型干眼症临床初步观察
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惠州市科技计划项目(No.2013Y065)


Preliminary clinical observation of Smart Plug canalicular plug for the treatment of aqueous-deficient dry eye
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Science and Technology Project of Huizhou City(No.2013Y065)

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    摘要:

    目的:探讨Smart Plug泪小管塞治疗水液缺乏型干眼症临床疗效。

    方法:选取2012-05/2013-04期间我院收治的48例水液缺乏型干眼症患者为研究对象,进行Smart Plug泪小管塞治疗,观察术后临床疗效、基础泪液分泌试验(Schirmer Ⅰ test,SⅠt)、泪膜破裂时间(tear break up time,BUT)、角膜荧光素染色(fluoreseein staining,FL)变化。

    结果:本组48例患者,显效31例(65%),有效14例(29%),无效3例(6%),总有效率为94%。治疗前,患者SⅠt,BUT,FL分别为3.49±1.24mm/5min,3.15±1.07s,2.52±0.11分。治疗后,患者SⅠt,BUT,FL均明显改善,与治疗前比较,差异具有统计学意义(P<0.05)。1例患者术后有异物感,8h后栓子脱落; 1例患者于术后8mo出现肉芽组织,泪小管塞脱落。其余病例无下泪小管感染或肉芽肿。

    结论:Smart Plug泪小管塞治疗水液缺乏型干眼症疗效确切,能够有效缓解临床症状,值得临床推广。

    Abstract:

    AIM: To discuss the effect of Smart Plug canalicular plug on aqueous-deficient dryeye.

    METHODS: Forty-eight cases of aqueous-deficient dry eye patients in our hospital from May 2012 to April 2013 were selected for the study. After treated by Smart Plug canalicular plug, postoperative clinical efficacy, foundation Schirmer I test(SIt), tear film break-up time(BUT), corneal fluorescein staining(FL)changes were observed.

    RESULTS: Forty-eight patients were cured, 31 cases were markedly effective(65%), effective 14 cases(29%), invalid in 3 cases(6%), the total effective rate was 94%. Before treatment, SⅠt, BUT, and FL was(3.49±1.24)mm/5min,(3.15±1.07)s, and(2.52±0.11)points, respectively. After treatment, SIt, BUT, FL were significantly improved compared with before treatment, the difference was statistically significant(P<0.05). One patient had postoperative foreign body sensation, 8h after shedding emboli; One patient granulation tissue after surgery 8mo, canalicular plug off. The remaining cases had no inferior lacrimal duct infection or granuloma.

    CONCLUSION:Smart Plug canalicular plug is an effective treatment for aqueous-deficient dry eye, can effectively relieve symptoms, worthy of promotion.

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陈晓莉,张世华,廖润斌. Smart Plug泪小管塞治疗水液缺乏型干眼症临床初步观察.国际眼科杂志, 2015,15(4):723-724.

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  • 收稿日期:2015-01-05
  • 最后修改日期:2015-03-25
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  • 在线发布日期: 2015-04-08
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