Abstract:AIM: To analyze the outcome of treating post-traumatic endophthalmitis in children.
METHODS: Twenty-four 2～11 year-old children(24 eyes)with post-traumatic endophthalmitis that presented to our hospital from June 2006 to Feburary 2014 were retrospectively analyzed. All cases were performed intravitreal injection of vancomycin(1mg/0.1mL)and ceftazidime(2.25mg/0.1mL)and dexamethasone(0.4mg/0.1mL)immediately after being identified. The second day after injection, 23 eyes were received lensectomy and vitrectomy with silicone oil(n=10)or C3F8(n=3)or clean air(n=8)or irrigating solution(n=2)tamponade. Only one eye was reinjected at 72h after the first injection. The visual outcomes were evaluated.
RESULTS: After follow-up 6～78mo, the inflammation of all cases were controled, 4 cases of eyeball atrophy(3 cases of silicone oil eye). Other 7 silicone oil filled eyes were received silicone oic extraction and IOL implantation. Twelve eyes presented with visual acuity of lower than 0.02, 4 eyes achieved 0.02～0.1, 4 eyes were 0.15～0.3,only 4 eyes reached 0.5～1.0. The final visual acuity improved in 16 eyes(70%), remained unchanged in 4 eyes(17%)and decreased in 3 eyes(13%). One case did not fit.
CONCLUSION: Early diagnosis of endophthalmitis in open-globe injury, intravitreal injection of antibiotics and vitrectomy can salvage more than a half of injuried eyes in children.
