AIM:To apply the PureVision Bandage contact lens in ophthalmology, observe the clinical effects and bandage lens used in persistent corneal epithelial defect, and assess the evaluation and significance of bandage lens in ocular surface disease therapeutic.

METHODS: Thirty patients(38 eyes)with persistent corneal epithelial defects wearing a bandage lens from 3d to 3mo were non-randomly selected. The results of corneal irritation symptoms, visual acuity, corneal epithelial healing and adverse circumstances during each period of before and after wearing bandage lens were observed.

RESULTS:For all 30 cases(38 eyes), complete remission(23 eyes, 61%), partial remission(11 eyes, 29%), effective rate 89%. Promote healing of corneal epithelium: healed completely(11 eyes, 29%), partially healed(21 eyes, 55%), effective rate 84.2%. The visual acuity was improved in 22 eyes, efficiency 58%.

CONCLUSION:Wearing bandage lens can effectively relieve the pain caused by corneal epithelial defect, protect corneal, maintain the local moisture, accelerate healing of persistent corneal epithelial lesions, and shorten the course of disease. It is a safe and effective method, and it can be widely used in clinical application and promoted in basic level hospital.