AIM:To evaluate the changes of corneal high-order aberration(including Coma, Spab, RMSh)after laser in situ keratomileusis(LASIK)with femtosecond laser, sub-Bowman keratomileusis(SBK)and laser epithelial keratomileusis(LASEK).

METHODS: Of 82 myopic patients(164 eyes), 31 patients(62 eyes)were treated by FS-LASIK, 31 patients(62 eyes)were treated by SBK, 20 patients(40 eyes)were treated by LASEK. Sirius system was used for measuring the coma aberration, spherical aberration, and high order aberration at 1, 15d,1, 3mo after surgery.

RESULTS: 1)Vision: The uncorrected visual acuity of the three groups had no differences(P>0.05). 2)Corneal aberrations: Three kinds of surgical procedure for patients with corneal aberration had significant impact. The C7, C8, C12 and RMSh of three groups were increased significantly(P<0.05). The C7, C8, C12 and RMSh were not recovered to preoperative levels after 3mo. But the increase of patients after FS-LASIK was smaller than the other two groups, with statistical significance(P<0.05).

CONCLUSION: Compared with SBK and LASEK,FS-LASIK has better visual acuity in the early postoperative and corneal higher-order aberrations increase is relatively small.