AIM: To evaluate the efficacy and safety of the internal limiting membrane(ILM)peeling combined with 23G vitrectomy for early treatment of foveoschisis with high myopia and explore more suitable operation methods.

METHODS: Twenty-nine high myopia patients(29 eyes)with foveoschisis in our hospital from January, 2013 to June, 2014 were selected and divided into two groups: the experimental group(15 eyes)was treated by 23G vitrectomy combined with ILM peeling and intraocular gas injection therapy, and the control group(14 eyes)was treated only with 23G vitrectomy combined with ILM peeling. The best spectacle-correction and foveoschisis reattachment were postoperatively followed up.

RESULTS:The best spectacle-correction and foveoschisis reattachment were improved significantly compared with preoperative in two groups(P<0.05). There was no significant difference between the two groups at postoperative(P>0.05).

CONCLUSION: 23G vitrectomy with ILM peeling is more effective for early treatment of foveoschisis with high myopia.