AIM: To compare the clinical effects between pars plana vitrectomy(PPV)and PPV with internal limiting membrane peeling(ILMP)for macular hole in high myopia eyes.

METHODS:The clinical data of 33 high myopia with macular hole patients(36 eyes)with or without retinal detachment caused by macular hole were retrospectively analyzed. The patients were divided into two groups according to different operation methods: 15 eyes in groupⅠhad undergone PPV; 21 eyes in groupⅡhad undergone PPV with ILMPP peeling. According to different conditions of patients,different auxiliary methods were accepted, such as silicone oil tamponade, C₃F₈ tamponade, photocoagulation, condensation, etc. The follow-up period was 3～12mo. Best corrected visual acuity(BCVA), macular hole closure rate and retinal reattachment rate were continuous checked after operation. Then we evaluated the outcome in the two groups by statistical analysis.

RESULTS: The postoperative mean BCVA increased by 0.167 in group Ⅰand 0.456 in group Ⅱ than preoperative, the difference was significant(t=2.46,6.753; P=0.027,0.000). And the difference of BCVA improvement was significant between those two groups(t=-2.943, P=0.006). The macular hole closed in 7 eyes(46.67%)in group Ⅰ,and 18 eyes(85.71%)in group Ⅱ; The difference was significant between those two groups(χ²=6.287,P=0.025).Retinal reattachment was found in 11 eyes(91.67%)in group Ⅰ and 19 eyes(94.73%)in group Ⅱ. The difference was not significant between the two groups(χ²=0.856, P=0.418).

CONCLUSION: PPV with ILMPP peeling for macular hole in high myopia eyes can obviously improve closure of macular hole and postoperative visual acuity. But the difference of retinal reattachment rate was not significant between peeling and unpeeling of ILMP.