AIM: To prove the clinical efficacy of double-incision operation of combining phacoemulsification and intraocular lens implantation and trabeculectomy with topical anesthesia.

METHODS: Fifty-four patients(60 eyes)with primary angle-closure glaucoma patients with cataract were randomly divided to single-incision group and double-incision group. Both were treated by phacoemulsification and intraocular lens implantation and trabeculectomy, followed up for 3mo. Intraoeular pressure(IOP), best corrected visual acuity(BCVA), inflammation of anterior chamber were observed.

RESULTS: 1)IOP: Postoperative, the average IOP had no statistical significance between two groups(P>0.05). 2)BCVA: the level of BCVA in double-incision group was 0.31±0.27 on 1d after surgery, single-incision group was 0.19±0.22, the differences had statistical significance(P<0.05). But on 1wk, 1, 3mo, the differences between two groups had no statistical significance(P>0.05). 3)Inflammation of anterior chamber after surgery: on 1d there were 9 eyes in double-incision group and 18 eyes in single-incision group, the differences had statistical significance(χ²=5.45, P<0.05). By anti-inflammatory treatment the differences between two groups had no statistical significance(P>0.05)on 1wk, 1, 3mo postoperative.

CONCLUSION: Double-incision operation of combining phacoemulsification and intraocular lens implantation and trabeculectomy is an effective and safe therapeutic method for patients with primary closed-angle glaucoma and cataract.