AIM: To study the risk factors of endophthalmitis after cataract surgery and prognosis of endophthalmitis after vitrectomy.

METHODS: One thousand nine hundred patients(1 900 eyes)of receiving cataract surgery in our hospital were selected and divided into infection group and control group according to the incidence of endophthalmitis. The influence of clinical index in the endophthalmitis after cataract surgery as well as related risk factors based on single factor and multi-factor Logistic regression was analyzed. All patients with endophthalmitis were received vitrectomy, and the prognosis of endophthalmitis after vitrectomy was observed.

RESULTS: Based on single factor analysis, the risk factors of endophthalmitis after cataract surgery including age, hypertension, diabetes mellitus, vitreous loss, operation time, common operating room and nonuse of anesthetics in the required time lead to the ocurrence of endophthalmitis after cataract surgery(P<0.05). Based on multi-factor Logistic regression, the independent risk factors of endophthalmitis after cataract surgery included age(≥70 years old), hypertension, diabetes mellitus, vitreous loss, operation time(≥10min), common operating room and nonuse of anesthetics in the required time(P<0.05). After vitrectomy, the vision of patients was significantly improved(P<0.05).

CONCLUSION: The risk factors of endophthalmitis after cataract surgery include age, hypertension, diabetes mellitus, vitreous loss, operation time, common operating room and nonuse of anesthetics in the required time. Vitrectomy can significantly improve the vision of patients.