AIM:To study the correlation of Cys C and blood lipid with diabetic retinopathy(DR).

METHODS:Sixty patients with DR from June 2011 to December 2014 were selected. According to international criteria, in the patients with DR, there were 28 cases without remarkable DR, 22 cases with mild, middle and sever nonproliferative diabetic retinopathy(NPDR), 10 cases with proliferative diabetic retinopathy(PDR).Sixty diabetic patients without DR were selected as NDR group. Sixty healthy people were selected as control group. Cys C, triglyceride(TG)and total cholesterol(TC)were detected.

RESULTS:In DR group, Cys C, TG and TC levels were higher than those in the NDR group and the control group, while in NDR group Cys C, TG and TC levels were higher than thoes in the control group, and the difference was statistically significant(P< 0.05). As DR aggravating, Cys C increased, and the difference was statistically significant(P<0.05). Cys C were positively correlated with the duration and blood lipid level(P<0.05).

CONCLUSION:Cys C changes abnormally in patients with DR, and with the progress of DR, Cys C trends to increase. The abnormal changes in DR patients positively associated with dyslipidemia.