AIM:To evaluate the effectiveness of laser peripheral iridoplasty combined with iridectomy in preclinical primary angle-closure glaucoma(PACG)by optical coherence tomography(OCT).

METHODS:Fifty-eight eyes of 31 patients with preclinical PACG were received laser peripheral iridoplasty combined with iridectomy. Images of anterior chamber angle in three different time(before treatment,1wk after treatment and 2mo after treatment)were collected by OCT. Anterior chamber depth(ACD), lens thickness(LT), chamber crowding rate(CCR)and lens position(LP)were measured by A-ultrasound.

RESULTS:Intraocular pressure(IOP), OA, ACD, CCR, LP were statistically significant differences in three different time(IOP:F=16.845, OA:F=30.498, ACD:F=38.705, CCR:F=86.671, LP:F=46.195; P<0.05), but not LT(F=0.756, P=0.471). However, there were statistically significant differences only in CCR but not in OA, ACD and LP(P=0.067, 0.359, 0.406)between 1wk after treatment group and 2mo after treatment group(P<0.05).

CONCLUSION:OCT can be used to monitor and quantify anterior chamber of PACG. CCR can be more sensitive to reflect structural changes of anterior chamber. LPI is an effective treatment for early PACG.