AIM:To compare the clinical efficacy of TransPRK and LASEK.

METHODS:This study included 120 patients(240 eyes)with high myopic, which were divided into TransPRK(60 patients with 120 eyes)group and LASEK group(60 patients with 120 eyes)randomly. Recovery status, visual acuity, haze condition and refractions of the two groups were compared respectively at 1, 2wk, 3mo and 1a.

RESULTS:The clinical results were very good for both groups. But at 1d post-operative, 86 eyes(71.7%)in TransPRK group felt no discomfort and had clear vision while there were 81 eyes(67.5%)in LASEK group having the same condition. One hundred and nine eyes(90.8%)had better UCVA than their BCVA pre-operative in TransPRK group compared to 87 eyes(72.5%)in LASEK group at 2wk post-operative. At 3mo post-operative, 113 eyes in TransPRK group had no haze(grade 0), compared to the 109 eyes in LASEK group.

CONCLUSION:TransPRK had faster recovery of visual acuity and less discomfort than LASEK. And rate of haze was statistically lower in TransPRK group(P<0.01). However, the visual acuity, refractions and vision quality at 1, 3, 6mo and 1a were not statistically different(P>0.05). Finally, there was no significant difference on the efficiency, safety and predictability of high myopia treatments between the two methods.