Abstract:Premacula hemorrhage can cause a sudden and dramatic loss of central vision. In some patients with premacula hemorrhage, the hemorrhage can be spontaneously resorbed, but in a slow-processing manner, and the toxic metabolites of resorbing process eventually cause permanent vision loss. Vitrectomy can effectively remove hemorrhage and improve vision. But its potential problematic complications and relatively high medical cost hinder the clinical application. Thus several non-vitrectomy techniques have gained attentions due to quickly vision recovering on treatment of premacula hemorrhage. In this article, we introduced and reviewed notable researches of non-vitrectomy techniques in recent years and their clinical applications.