AIM:To detect the related biochemical indicators of the Uygur and Han patients with diabetic retinopathy,to judge progression of diabetic retinopathy and evaluate the relation between ethnic and progression. So as to give a more accurate guide for regional clinical treatment, early detection, early prevention, reduce concurrency disease and improve quality of life.

METHODS:One hundred and twenty patients with diabetic retinopathy aged 38～70 were diagnosed by fundus fluorescein angiography, including 60 patients with non-proliferative diabetic retinopathy(NPDR), 30 Uygur and Han respectively(devided into Uygur group 1, Han group 1); 60 patients with proliferative diabetic retinopathy(PDR), 30 Uygur and Han respectively(devided into Uygur group 2, Han group 2). All patients were detected for high-sensitivity C-reactive protein(hs-CRP), serum total bilirubin(TBIL), fibrinogen(FIB), D-dimer(DD)indicators using fasting blood.

RESULTS:Regardless of ethnic, NPDR group and PDR group were significant differences in the four indicators; there was no significant difference between the Han and the Uygur group on the hs-CRP. But for the TBIL, FIB and DD, it was significantly different between the two ethnical groups, and it was more obvious in Uygur group.

CONCLUSION:Diabetic retinopathy generally was more severe in Xinjiang Uygur groups, more attention should be paid in clinical practice.