AIM:To investigate the effect of rigid gas permeable lenses(RGP)for the difference of spherical equivalent(△_SE)and the difference of axial length(△_AL)in children with non-amblyopia anisometropia.

METHODS:In department of optometry in our hospital, 95 children 190 eyes aged from 6～12 year-old with hyperopic refractive error, of whom the difference of spherical equivalent between two eyes was 1D≤△_SE<2.0D and whose corrected vision was different, but the corrected visual acuity of either right eye or left eye was within the normal range of children with the same age, which meant the difference was non-amblyopia. The patients were randomly divided into two groups:48 cases in group A, in which group the eye with stronger diopter(poorer eye sight eye)wore RGP, the other eye without wearing lenses; 47 cases in group B, in which group children did not wear lenses as a control group. Cyclopentanone with 1% concentration was used to mydriasis, then spherical equivalent(SE)refraction was calculated, the axial length(AL)was measured, and follow-up lasted for 1.5a. The △_SE and △_AL of the two groups were calculated and analyzed statistically.

RESULTS:The △_SE between two eyes of group A was less than that of group B, and the difference was statistically significant(F=18.508,P=0.002<0.05); the △_AL between two eyes of group A was less than that of group B, the difference was statistically significant(F=1116.765,P=0.000<0.05).

CONCLUSION:In children with non-amblyopia anisometropia, RGP is very necessary to correct the vision of higher-dioptry eye. And it can significantly reduce the binocular refraction, correct anisometropia, avoid visual function abnormalities caused by anisometropia and so on.