AIM: To observe the clinical effects of 23-G micro-incision vitrectomy combined with 1.8mm micro-incision phacoemulsification and immediate intraocular lens(IOL)implantation.

METHODS: A retrospective analysis were done in 48 patients with 54 eyes from September 2014 to March 2015 in our hospital who received micro-incision vitrectomy combined with micro-incision phacoemulsification and immediate IOL implantation. Best corrected visual acuity(BCVA), intraocular pressure(IOP), corneal astigmatism and corneal endothelial cells were recorded before and at 1d, 1 and 3mo after operations. All patients were followed up to observe the fundus, IOL position and postoperative low IOP, corneal edema, posterior capsular opacification, ocular hypertension and other complications.

RESULTS: All procedures were successfully completed. After 3mo, BCVA increased in 49 eyes(91%)compared to that preoperative. Visual acuity did not improve in 5 eye(9%), and no visual acuity decreased. The differences on IOP and corneal endothelial cells before and after operation were significant(P<0.01). The percentage of lost corneal endothelial cells was 11.71±8.12% at 3mo. At early stage postoperatively corneal astigmatism increased(P<0.05)and there was no difference between that pre-operative and 3mo post-operatively(P>0.05).There were 6 eyes with transient high IOP(IOP greater than 25mmhg in 1mo), 7 eyes with corneal edema at early stage, 2 eyes with formed exudation in anterior chamber, and there were 3 eyes with posterior capsular opacification, in which 2 eyes were performed with YAG laser for posterior capsulotomy and whose visual acuity improved significantly. There was no retinal detachment, choroidal detachment, endophthalmitis, neovascular glaucoma, hypotony, IOL misalignment or dislocation.

CONCLUSION: Micro-incision vitrectomy combined with micro-incision phacoemulsification and immediate IOL implantation is a safe and effective method with wide application, small damage, rapid recovery and less complication, and it is worth of promotion.