AIM:To investigate the effect of a Chinese medicine(Qi Ming granule)on the retinal and choroidal circulation in diabetes patients.

METHODS: According to the results of fundus fluorescein angiography(FFA), all the 45 diabetes patients were divided into no diabetic retinopathy(NDR)group and nonproliferative diabetic retinopathy(NPDR)group. All subjects were examined by FFA and indocyanine green angiography(ICGA)at the same time. After taken Qi Ming granule for 3mo, all subjects were examined by the same method. FFA and ICGA were used to evaluate the retinal and choroidal circulation and their features. The key points were filling time for the retinal and choroidal circulation before and after treatments. The accuracy data was used to evaluate the effect.

RESULTS: After taken Qi Ming granule for 3mo, there were significant decrease of the retina and the choroid filling time in NDR and NPDR groups. The occurrence rate of various abnormal angiographic features were significantly decreased.

CONCLUSION: Qi Ming granule can accelerate the blood flow of retina and choroid, improve the blood circulation in diabetes patients, and delay the occurrence and development of diabetic retinopathy.