Abstract:AIM:To study the clinical effect of trabeculectomy combined with mitomycin and retinal condensation on neovascular glaucoma and their influence on ocular hemodynamics.
METHODS:A total of 45 patients(45 eyes)with neovascular glaucoma treated with trabeculectomy, mitomycin and retinal condensation were selected, and the postoperative clinical effect, visual acuity, intraocular pressure(IOP)and complications were observed. The color Doppler imaging technique was used to detect hemodynamics index of contralateral and ipsilateral eye before and 2wk after surgeries.
RESULTS:All the patients were followed up for 3~6mo. The successful rate was 84%, the rate of forming functional filtering bleb was 82%, and the complication rate was 27%. The IOP at 1, 3 and 6mo after surgeries decreased significantly compared with pre-operation(P<0.05), and the corrected visual acuity improved significantly at 1, 3 and 6mo after treatments(P<0.05); at 1, 3 and 6mo after treatments, the hemodynamic parameters including PSV, EDV, RI of ipsilateral eye improved significantly compared with those before surgeries(P<0.05).
CONCLUSION:Trabeculectomy combined with mitomycin and retinal condensation has high success rate on treating neovascular glaucoma, which can effectively control IOP, improve vision and ocular hemodynamics.