AIM:To observe the clinical effect of comprehensive operation for neovascular glaucoma(NVC).

METHODS:Thirty-nine cases(39 eyes)with late neovascular glaucoma in our hospital from October 2010 to October 2013 were treated with cyclocryotherapy, retina condensation combined with trabeculectomy and anterior vitrectomy. The clinical data were retrospectively analyzed.

RESULTS:All the patients were followed up for 6～12mo. The mean postoperative intraocular pressure(IOP)of 39 cases(39 eyes)was 12.94±2.33mmHg(1mmHg=0.133kPa)at 1wk, compared with preoperative IOP(57.31±6.72mmHg), which was decreased obviously. The pain was alleviated. During follow-up period, IOP of 35 eyes was normal(17.25±2.24mmHg)without using IOP-lowing drugs and the postoperative IOP was decreased to the normal range after using 1～2 kinds of drugs in 4 cases. The iris neovascularization of all patients eliminated at different extent. Conjunctival filtering blebs of 34 cases were dispersion and those of 5 cases were flat. No shallow anterior chamber or eyeball atrophy occurred during follow-up period.

CONCLUSION:The therapy of cyclocryotherapy, retina condensation combined with trabeculectomy and anterior vitrectomy is safe and effective to reduce IOP and relieve suffering in patients with NVG.