AIM:To investigate the clinical efficacy of Chinese medicine formula for macular edema in the patients with phlegm intrinsic type and central serous chorioretinopathy(CSCR).

METHODS:With randomized controlled method,56 cases(71 eyes)with phlegm intrinsic type and CSCR were randomly divided into the control group and the treatment group.The control group included 28 cases(35 eyes),and the treatment group 28 cases(36 eyes).The patients in the control group received injections of 2mL compound anisodine beside superficial temporal artery,once a day.Based the above treatment,the patients in the treatment group were given 10g oral Chinese medicine formula for macular edema,twice a day.After 3mo,the overall curative effect,visual acuity,visual field mean sensitivity and the OCT in both groups were measured and evaluated.

RESULTS:After treatment,the total effective rate in treatment group was 89%,which was significantly higher than 79% in the control group(P< 0.05).Compared with the control group,the vision and visual field mean sensitivity in the treatment group significantly increased,and macular center thickness of 1mm diameter range,the average thickness of the macular area of 6mm diameter and the diameter and the central area and the total macular volume were statistically significantly lower(P<0.05).

CONCLUSION:Chinese medicine formula for macular edema may ameliorate the visual acuity and visual field in the patients with phlegm intrinsic type and central serous chorioretinopathy,reducing edema lesions and promoting the recovery of visual function.