AIM:To investigate the effect of orthokeratology on vision and corneal shape change in myopic adolescents.

METHODS:Ninety-seven young patients(176 eyes)with myopia wearing orthokeratology were randomly selected. Spherical equivalent(SE), uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), corneal curvature and central corneal thickness were examined before, after wearing at 1d, 1wk, 1, 3 and 6mo. The results were compared and analyzed.

RESULTS:SE decreased and UCVA increased at 1d, 1wk, 1, 3 and 6mo after wearing orthokeratology, the difference was statistically significant(P<0.05)when compared with before wearing. The difference of BCVA after wearing orthokeratology compared with before has no statistics significant(P>0.05). The difference of corneal curvature after wearing orthokeratology for 1d, 1wk, 1, 3 and 6mo compared with before was statistically significant(P<0.05). The central corneal thickness became thiner after wearing orthokeratology for 1wk, and the central corneal thickness after wearing orthokeratology for 1, 3, 6mo compared with before was statistically significant(P<0.05).

CONCLUSION:Orthokeratology can effectively reduce the degree of myopia, and significantly improve the uncorrected visual acuity.