AIM:To investigate the effect of orthokeratology for teenager with mild to moderate myopia and the safety and effectivity of orthokeratology.

METHODS:Totally 85 patients(165 eyes, aging from 12 to 18 years old)received orthokeratolog lens treatment in our hospital from January 2014 to February 2015 were followed up for 6mo. All patients wore orthokeratology lens for 8-10h in night after standard optometry for spectacles. The visual acuity, corneal curvature, diopter, the ocular axial length and the central corneal thickness were observed, as well as the corneal endothelial cell density, coefficient of variation and the hexagonal cell ratio.

RESULTS:Followed-up for 6mo, the uncorrected visual acuity, the corneal curvature and the diopter were changed compared before wearing(P<0.05). There was no significant differences on the axial length, the central corneal thickness, the central corneal endothelial cell density, coefficient of variation or the hexagonal cell ratio before and after wearing(P>0.05). Almost all patients felt favorable after 6mo wearing. Only a few patients had a mirror patch corneal epithelium desquamation, conjunctivitis, etc and all could be restored after therapy.

CONCLUSION:Orthokeratology lenses are safe and effective for treating mild and middle myopia in teenagers. But the further study and followed-up are needed for long term wearing.