AIM: To study correcting effect and visual quality after laser-assisted in situ keratomileusis(LASIK)with femtosecond and posterior chamber intraocular lens(ICL)implantation in high myopia patients.

METHODS: Fifty-five patients(106 eyes)with high myopia from February 2012 to February 2015 in our hospital were analyzed. According to the different operation, patients were divided into the observation group(using ICL implantation, 27 cases with 53 eyes)and the control group(using LASIK, 28 cases with 53 eyes). Postoperative follow-up was 1a, to observe and analyze the visual quality, higher order aberration and complications of two groups.

RESULTS: Uncorrected visual acuity(UCVA), the best corrected visual acuity(BCVA), effectiveness index and security index at 1a postoperatively of observation group, were 1.04±0.86(LogMAR), 0.97±0.19(LogMAR), 104.69±18.56, 108.79±17.68, significantly higher than those of control group 0.78±0.11(LogMAR), 1.04±0.09(LogMAR), 93.78±15.65, 100.71±11.68(P<0.05). And observation group in the two kinds of light and shade environment at various spatial frequency contrast sensitivity were higher than the control group. Those under the light environment at 1.5, 3, 6, 12 c/d and under dark environment at 1.5, 3, 6, 18 c/d compared were different between the two groups(P<0.05). Spherical aberration and comatic aberration of observation group at 1a after operation were lower than those of control group(P<0.05). The difference of trefoil between the two groups was not significant(P>0.05). No severe complications were observed in both groups.

CONCLUSION: LASIK with femtosecond and ICL lens implantation can effectively improve the patient's visual quality, but for patients with high myopia, ICL lens implantation effect is more significant, the safety index of ICL implantation, as well as the effectiveness index and the visual quality are better than those of LASIK.