康柏西普玻璃体腔注射治疗渗出型老年性黄斑变性的疗效
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Clinical observation of intravitreal injection of Conbercept treating exudative age-related macular degeneration
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    摘要:

    目的:观察玻璃体腔内注射康柏西普治疗渗出型老年黄斑变性的临床疗效。

    方法:前瞻性研究。渗出型老年黄斑变性患者112例112眼,随机分为研究组和对照组,各56例56眼,研究组患者采用玻璃体腔内注射康柏西普治疗,对照组采用保守治疗,观察治疗前后两组患者裸眼视力及黄斑中心凹视网膜厚度。

    结果:研究组患者治疗后视力明显提高,且治疗后6mo提高最明显。研究组患者治疗后黄斑中心凹视网膜厚度均减低,且治疗后6mo减低最明显。

    结论:玻璃体腔内注射康柏西普能有效提高渗出型老年黄斑变性患者视力,降低黄斑中心凹厚度。

    Abstract:

    AIM: To observe clinical efficacy of the intravitreal injection of conbercept treatment for exudative age-related macular degeneration.

    METHODS:Prospective study. Totally 112 senile patients(112 eyes)with exudative macular degeneration were randomly divided into study group and the control group, 56 cases in each group. The study group were treated with intravitreal injection of conbercept. The control group received conservative treatment. Uncorrected visual acuity and foveal retinal thickness were observed before and after treatment in the two groups.

    RESULTS: Visual acuity of study group improved significantly, and the most obvious improvement was observed at 6mo after treatment. Foveal retinal thickness of study group was reduced after treatment, and the most obvious decrease was observed at 6mo after treatment.

    CONCLUSION: Intravitreal injection of conbercept can improve visual acuity reduced foveal thickness in senile patients with exudative age-related macular degeneration.

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宋蔚,赵帅,郅瑛,等.康柏西普玻璃体腔注射治疗渗出型老年性黄斑变性的疗效.国际眼科杂志, 2016,16(7):1310-1312.

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  • 收稿日期:2016-04-10
  • 最后修改日期:2016-06-02
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  • 在线发布日期: 2016-06-29
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