AIM: To study the efficacy and safety of Ultra Q-YAG vitreolysis for vitreous floaters.

METHODS: Retrospective case series study. From September 2014 to May 2015 in Beijing Aier-Intech Eye Hospital, 263 cases(340 eyes)with vitreous floaters were involved. All patients underwent visual acuity, intraocular pressure, slit lamp, mydriatic fundus, B ultrasonic examination, and recorded the form of a vitreous opacity excluded pathological fundus lesions. All the patients were divided into two groups: Group A(<30 years old)78 cases(82 eyes); the morphology of vitreous opacity were dot, filiform and mesh. Group B(>45 years old), 185 cases(258 eyes), the morphology of vitreous opacity was Weiss ring, translucent flocculent clouds or dense fibrous membrane. Patients in 30-45 years old were eliminated because of the untypical opacity factor. The treatment was done by the same physician. Vision changes was analyzed before and after the treatment.

RESULTS: Questionnaire survey was done. According to the scores of the questionnaires, patients were divided into 3 groups: no improvement(1-2 points), partial improvement(3-5 points), significant improvement(6-10 points). At 1mo after treatment, Group A: no improvement in 9 eyes(11.0%), partial improvement in 57 eyes(69.5%)and significant improvement in 16 eyes(19.5%); Group B: no improvement in 0 eyes, partial improvement in 23 eyes(8.9%)and significant improvement in 235 eyes(91.1%); all the patients had no complications.

CONCLUSION: The treatment with YAG vitreolysis for vitreous floaters is safe and effective, especially for the patients more than 45 years old whose vitreous floaters caused by posterior vitreous detachment.