AIM: To compare the coherence and difference on the fundus examination made with two kinds of optical coherence tomography(OCT): Angio-OCT and fourier domain-optical coherence tomography(FD-OCT).

METHODS: Using Angio-OCT and FD-OCT to measure the retinal nerve fiber layer(RNFL)thickness, optic parameters, and ganglion cell complexes(GCC)thickness from 20 subjects respectively. The coherence was tested with Pearson's correlation coefficient, the difference was tested with paired Student t testing.

RESULTS: The total correlation of the RNFL thickness, optic parameters, GCC thickness made with two kinds of OCT was between 0.7-0.8; the RNFL thickness, optic disk area etc. made with the Angio-OCT were lower than those made with FD-OCT except for the GCC thickness.

CONCLUSION: The results made with two kinds of OCT from the same subject has certain coherence, but cannot be compared directly.