AIM: To investigate the prenatal risk factors for retinopathy of prematurity(ROP)in Kunming Children's Hospital.

METHODS: One thousand and one hundred cases of prematurity and infants(May 2010 to Dec. 2014)with birth weight less than 2 000g were examined by Retcam II and recorded the stage and risk factors.

RESULTS: One hundred and thirty-nine ROP patients were founded among the 1 010 cases(13.76%), including 80 cases(57.55%)in Stage 1, 42 cases(30.22%)in Stage 2, 9 cases(6.47%)in Stage 3, 4 cases(2.88%)in Stage 4, 4 cases(2.88%)in Stage 5. Nine cases(6.47%)were threshold ROP. There was significant difference in birth weight(BW), gestational age(GA), multiple pregnancy and ischemia between ROP and Non-ROP groups. GA and BW, multiple pregnancy and ischemia were significant risk factors associated with ROP.

CONCLUSION:In Kunming Children's Hospital, the incidence of ROP is 13.67%. Low birth-weight and low gestational ages, multiple pregnancy and ischemia are main maternal risk factors for ROP.